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N. M. Valenzuela, L. Hong, X.-Da Shen, F. Gao, S. H. Young, E. Rozengurt, J. W. Kupiec-Weglinski, M. C. Fishbein and E. F. Reed Blockade of P-Selectin Is Sufficient to Reduce MHC I Antibody-Elicited Monocyte Recruitment In Vitro and In Vivo American Journal of Transplantation 13

Version of Record online: 27 DEC 2012 | DOI: 10.1111/ajt.12016

The authors demonstrate that donor class I-specific antibody elicits endothelial exocytosis and P-selectindependent monocyte recruitment, and that the P-selectin antagonist rPSGL-1-Ig curbs macrophage accumulation in a murine cardiac allograft in response to these antibodies.

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