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S. Bunnapradist, K. Ciechanowski, P. West-Thielke, S. Mulgaonkar, L. Rostaing, B. Vasudev, K. Budde and on behalf of the MELT investigators Conversion From Twice-Daily Tacrolimus to Once-Daily Extended Release Tacrolimus (LCPT): The Phase III Randomized MELT Trial American Journal of Transplantation 13

Version of Record online: 21 DEC 2012 | DOI: 10.1111/ajt.12035

This phase III noninferiority conversion trial in stable renal transplant recipients demonstrates that a novel extended-release once-daily tacrolimus formulation is noninferior to tacrolimus twice-daily in efficacy failure rates, has a similar safety profile, and requires lower doses to achieve target trough levels.

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