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F. Haspot, H. W. Li, C. L. Lucas, T. Fehr, S. Beyaz and M. Sykes Allospecific Rejection of MHC Class I-Deficient Bone Marrow by CD8 T Cells American Journal of Transplantation 14

Version of Record online: 4 DEC 2013 | DOI: 10.1111/ajt.12525

In a nonmyeloablative mouse bone marrow transplant model, the authors observe that recipient CD8 T cells specifically reject allogeneic, but not syngeneic, marrow lacking MHC class I heavy or light chains, in a manner that implicates indirect allorecognition through a TCR-independent recognition pathway.

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