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S.S. Alessi, M.M.S. Nico, J.D. Fernandes and S.V. Lourenço Reflectance confocal microscopy as a new tool in the in vivo evaluation of desquamative gingivitis: patterns in mucous membrane pemphigoid, pemphigus vulgaris and oral lichen planus British Journal of Dermatology 168

Version of Record online: 20 NOV 2012 | DOI: 10.1111/bjd.12021

What’s already known about this topic?

  • Reflectance confocal microscopy (RCM) is beginning to be studied in inflammatory and blistering skin diseases. However, use of this method has not been studied in the mucosal manifestations of such diseases.
  • Desquamative gingivitis is a peculiar clinical manifestation of pemphigus vulgaris, mucous membrane pemphigoid and lichen planus that presents difficulties in diagnosis.

What does this study add?

  • This study is the first to show RCM images of gingival lesions.
  • Our findings correlated closely with the histopathological findings of pemphigus vulgaris, mucous membrane pemphigoid and lichen planus.

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