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J.J. Keller, C.-S. Wu and H.-C. Lin Increased risk of psoriasis following chronic rhinosinusitis without nasal polyps: a population-based matched-cohort study British Journal of Dermatology 168

Article first published online: 13 DEC 2012 | DOI: 10.1111/bjd.12047

What’s already known about this topic?

  •  Although chronic rhinosinusitis without nasal polyps (CRSsNP) and psoriasis both share immunological disturbances as pathological factors, no study has investigated the risk for psoriasis among patients with CRSsNP.
  •  Only two studies investigating the immune responses of these conditions have been conducted to date.

What does this study add?

  •  The incidence rate of psoriasis during the 5-year follow-up period was 1·41 [95% confidence interval (CI) 1·14–1·71] per 1000 person-years and 0·69 (95% CI 0·59–0·81) per 1000 person-years for subjects with and without CRSsNP, respectively.
  •  The adjusted hazard ratio for psoriasis during the 5-year follow-up period for subjects with CRSsNP compared with controls was 2·01 (95% CI 1·54–2·62).

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