J.J. Keller, C.-S. Wu and H.-C. Lin Increased risk of psoriasis following chronic rhinosinusitis without nasal polyps: a population-based matched-cohort study British Journal of Dermatology 168
What’s already known about this topic?
Although chronic rhinosinusitis without nasal polyps (CRSsNP) and psoriasis both share immunological disturbances as pathological factors, no study has investigated the risk for psoriasis among patients with CRSsNP.
Only two studies investigating the immune responses of these conditions have been conducted to date.
What does this study add?
The incidence rate of psoriasis during the 5-year follow-up period was 1·41 [95% confidence interval (CI) 1·14–1·71] per 1000 person-years and 0·69 (95% CI 0·59–0·81) per 1000 person-years for subjects with and without CRSsNP, respectively.
The adjusted hazard ratio for psoriasis during the 5-year follow-up period for subjects with CRSsNP compared with controls was 2·01 (95% CI 1·54–2·62).
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