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J.L. Blok, S. van Hattem, M.F. Jonkman and B. Horváth Systemic therapy with immunosuppressive agents and retinoids in hidradenitis suppurativa: a systematic review British Journal of Dermatology 168

Article first published online: 30 JAN 2013 | DOI: 10.1111/bjd.12104

What’s already known about this topic?

  • The immune system is important in the pathogenesis of hidradenitis suppurativa (HS).
  • Treatment of HS is difficult and usually comprises antibiotics, antiandrogens, laser treatment or surgery.
  • Systemic immunosuppressive and retinoid therapies are frequently prescribed; however, little is known about which agents are most effective.

What does this study add?

  • Infliximab, adalimumab and acitretin are the most effective systemic agents, although the quality of evidence for acitretin is lower than that for infliximab and adalimumab.

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