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Y.E. Zhao, J.X. Ma, L. Hu, S.X. Xiao and Y.L. Zhao Meta-analysis of the association between psoriasis and human leucocyte antigen-B British Journal of Dermatology 169

Version of Record online: 13 AUG 2013 | DOI: 10.1111/bjd.12387

What's already known about this topic?

  • Various alleles of human leucocyte antigen (HLA)-B have been reported to be associated with psoriasis, but studies of the alleles have been carried out mostly in small populations and the results from different studies are not consistent.

What does this study add?

  • This study is the first meta-analysis on the association between HLA-B and psoriasis.
  • This study has indentified 26 susceptibility alleles, 24 protective ones and 10 unassociated alleles out of the 60 psoriasis-associated HLA-B alleles reported before.
  • The HLA-B alleles associate with psoriasis to different degrees in different races and clinical types.

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