T. Tsakok, T.M. McKeever, L. Yeo and C. Flohr Does early life exposure to antibiotics increase the risk of eczema? A systematic review British Journal of Dermatology 169
What's already known about this topic?
A number of studies have suggested that early life exposure to antibiotics may lead to an increased risk of subsequent eczema.
The evidence to date is conflicting and no systematic review has been conducted.
What does this study add?
- Antibiotic exposure in early life may increase the risk of subsequent eczema by up to 40%, with broad-spectrum antibiotics having a more pronounced effect.
- Each additional antibiotic course may confer a further 7% risk increase.
- Antibiotics should be prescribed with caution, especially in high-risk children.
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