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M. Ghannoum, N. Isham and V. Catalano A second look at efficacy criteria for onychomycosis: clinical and mycological cure British Journal of Dermatology 170

Version of Record online: 13 JAN 2014 | DOI: 10.1111/bjd.12594

What's already known about this topic?

  • Onychomycosis mycological cure is currently defined as a negative KOH and negative dermatophyte culture.

What does this study add?

  • The current definition of onychomycosis complete cure is too stringent.
  • Microscopy of late-visit samples may demonstrate nonviable hyphae.
  • Onychomycosis cure should be defined as the absence of clinical signs or presence of negative culture, with or without negative microscopy, assessed after an adequate washout period.

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