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Yuichiro Nakashima, Keiji Yoshinaga, Hiroyuki Kitao, Koji Ando, Yasue Kimura, Hiroshi Saeki, Eiji Oki, Masaru Morita, Yoshihiro Kakeji, Minako Hirahashi, Yoshinao Oda and Yoshihiko Maehara Podoplanin is expressed at the invasive front of esophageal squamous cell carcinomas and is involved in collective cell invasion Cancer Science 104

Article first published online: 22 OCT 2013 | DOI: 10.1111/cas.12286

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We focused on the expression of podoplanin in esophageal squamous cell carcinoma and inestigated the correlation of podoplanin and epithelial-mesenchymal transition. Podoplanin was significantly associated with and likely contibutes to the invasion of esophageal squamous cell caricinoma in absence of epithelial mesenchymal transition.

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