Dandan Zhang, Yan Wang, Lina Dong, Yangang Huang, Jing Yuan, Wei Ben, Yang Yang, Ning Ning, Meisong Lu and Yongmei Guan Therapeutic role of EF24 targeting glucose transporter 1-mediated metabolism and metastasis in ovarian cancer cells Cancer Science 104
We report in this study the inhibition effect of EF24 against the energy metabolism in ovarian cancer cells and tumors through the down-regulation of Glut1 expression. This effect may further lead to the inhibition of cell migration, invasion and tumor metastasis. Therefore, EF24 is likely a possible candidate for anti-metastasis therapeutic applications for ovarian cancer.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf