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Jing-Lei Liu, Guang-Zhi Zeng, Xiao-Li Liu, Yong-Qiang Liu, Zhong-Guo Hu, Ying Liu, Ning-Hua Tan and Guang-Biao Zhou Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells Cancer Science 104

Article first published online: 8 NOV 2013 | DOI: 10.1111/cas.12295

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A natural compound bigelovin arrests cell cycle at S phase by triggering proteolysis of oncoprotein E2F1, which is overexpressed in multiple myeloma cells.

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