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Takahiro Koyanagi, Yasuhiro Suzuki, Yasushi Saga, Shizuo Machida, Yuji Takei, Hiroyuki Fujiwara, Mitsuaki Suzuki and Yasufumi Sato In vivo delivery of siRNA targeting vasohibin-2 decreases tumor angiogenesis and suppresses tumor growth in ovarian cancer Cancer Science 104

Version of Record online: 8 NOV 2013 | DOI: 10.1111/cas.12297

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Administration of siRNA targeting a novel angiogenesis stimulator, vasohibin-2, with atelocollagen biomaterial retarded ovarian tumor growth through decrease of angiogenesis and acceleration of vascular normalization. These results demonstrated the effectiveness of molecular targeting of vasohibin-2 in ovarian cancer.

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