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Xiaojian Ni, Tiansong Xia, Yingchun Zhao, Wenbin Zhou, Naping Wu, Xiaoan Liu, Qiang Ding, Xiaoming Zha, Jiahao Sha and Shui Wang Downregulation of miR-106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2 Cancer Science 105

Version of Record online: 4 DEC 2013 | DOI: 10.1111/cas.12309

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MMP2 upregulation plays an important role in BC bone metastasis through ERK pathways, and miR-106b directly regulates MMP2 expression. The miR-106b/MMP2/ERK pathway may be a promising therapeutic target for inhibiting BC bone metastasis.

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