Huangang Jiang, Hong Zhao, Hui Xu, Liu Hu, Wenbo Wang, Yuehua Wei, You Wang, Xiaohong Peng and Fuxiang Zhou Peripheral blood mitochondrial DNA content, A10398G polymorphism, and risk of breast cancer in a Han Chinese population Cancer Science 105
Our finding suggested that the peripheral blood mtDNA content might be potentially used as a tool to estimate risk of breast cancer for selected Chinese women. The risk of breast cancer was associated with decreased mtDNA content in premenstrual women. On the contrary, increased mtDNA content is associated with breast cancer risk in aged and postmenopausal women.
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