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Jianhong Wang, Ruihong Gao, Qian Li, Songqiang Xie, Jin Zhao and Chaojie Wang Synthesis, Cytotoxicity, and Cell Death Profile of Polyaminoanthraquinones as Antitumor Agents Chemical Biology & Drug Design 80

Article first published online: 9 OCT 2012 | DOI: 10.1111/cbdd.12038

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Several polyaminoanthraquinones were synthesized and evaluated for antitumor efficiency. The intracellular pharmacological behaviors of 9b and 9c (i.e., mitochondria-mediated cell apoptotic death and necrosis) were further elucidated.

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