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Pavel N. Solyev, Alexander V. Shipitsin, Inna L. Karpenko, Dmitry N. Nosik, Ludmila B. Kalnina, Sergey N. Kochetkov, Marina K. Kukhanova and Maxim V. Jasko Synthesis and Anti-HIV Properties of New Carbamate Prodrugs of AZT Chemical Biology & Drug Design 80

Article first published online: 9 OCT 2012 | DOI: 10.1111/cbdd.12047

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A series of new 5′-O-carbamate prodrugs of AZT have been prepared. The stability in biological media, anti-HIV properties and pharmocokinetic parameters in dogs were evaluated.

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