E-mail

E-mail a Wiley Online Library Link

Monika Sharma, Sowmya Garigipati, Binita Kundu, Deekshith Vanamala, Arvind Semwal, Dharmarajan Sriram and Perumal Yogeeswari Discovery of Novel 1,2,4-Triazol-5-Ones as Tumor Necrosis Factor-Alpha Inhibitors for the Treatment of Neuropathic Pain Chemical Biology & Drug Design 80

Version of Record online: 9 OCT 2012 | DOI: 10.1111/cbdd.12049

Thumbnail image of graphical abstract

In the present work, synthetic integration of substituted semicarbazides and various aliphatic, aryl and heteroaryl acids into 1,2,4-triazol-5-ones was accomplished. The compounds suppressed the inflammatory component of the neuropathic pain inhibiting TNF-α and preventing oxidative and nitrosative stress.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH