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Laleh Alisaraie, Yangxin Fu and Jack A. Tuszynski Dynamic Change of Heme Environment in Soluble Guanylate Cyclase and Complexation of NO-Independent Drug Agents with H-NOX Domain Chemical Biology & Drug Design 81

Version of Record online: 26 DEC 2012 | DOI: 10.1111/cbdd.12082

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Dynamic conformational changes of the soluble Guanylate Cyclase (sGC) in complex with heme, and NO-independent activators are studied. As well, a new alternative binding site is introduced.

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