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Bahaa El-Dien M. El-Gendy, Ebrahim H. Ghazvini Zadeh, Ania C. Sotuyo, Girinath G. Pillai and Alan R. Katritzky α-Substitution Effects on the Ease of S[RIGHTWARDS ARROW]N-Acyl Transfer in Aminothioesters Chemical Biology & Drug Design 81

Version of Record online: 24 APR 2013 | DOI: 10.1111/cbdd.12092

Thumbnail image of graphical abstract

Spatial distance, b(N-C), between the terminal amine and the thioester carbon is shortened by α-C(O)X (X = OH, OMe, NH2) substituents.

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