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Jian-Lan Jiang, Xin Su, Huan Zhang, Xiao-Hang Zhang and Ying-Jin Yuan A Novel Approach to Active Compounds Identification Based on Support Vector Regression Model and Mean Impact Value Chemical Biology & Drug Design 81

Version of Record online: 4 APR 2013 | DOI: 10.1111/cbdd.12111

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We handled a nonlinear case using a well-trained SVR model based on MIV. Eight constituents with significant cytotoxicity were identified from Curcuma longa L. prior to bioassay-guided separation. The cytotoxicity of the constituents was partly confirmed by the MTT assays and the previous reports.

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