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Yanlan Liu, Hongbo Tan, Hong Yan and Xiuqing Song Design, Synthesis and Biological Evaluation of 3,9-diazatetraasteranes as Novel Matrilysin Inhibitors Chemical Biology & Drug Design 82

Article first published online: 8 AUG 2013 | DOI: 10.1111/cbdd.12185

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A series of 3,9-diazatetraasteranes was designed and synthesized as matrilysin inhibitors. These compounds were evaluated for their inhibitory activity against A549 (small cell lung cancer) cells and displayed potent activities.

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