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Celia Herrera-Rincon, Carlos Torets, Abel Sanchez-Jimenez, Carlos Avendaño and Fivos Panetsos Chronic electrical stimulation of transected peripheral nerves preserves anatomy and function in the primary somatosensory cortex European Journal of Neuroscience 36

Article first published online: 24 SEP 2012 | DOI: 10.1111/ejn.12000

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Rat barrel cortex. Intact animals show similar activity, cortical volume and number of GABA-ergic neurons in the two somatosensory cortices (top). Complete transection of the infraorbital nerve reduces activity, volume and number of neurons in the deafferented cortex (middle). Chronic electrical stimulation of the stump after irreversible transection of the nerve has neuroprotective effects to the deafferented cortex: the two cortices are similar resembling the control ones (bottom).

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