Elisa J. Hoekstra, Lars von Oerthel, Annemarie J. A. van der Linden, Raymond D. Schellevis, Gerard Scheppink, Frank C. P. Holstege, Marian J. Groot-Koerkamp, Lars P. van der Heide and Marten P. Smidt Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons European Journal of Neuroscience 37
Microarray analysis of an LMX1A overexpression cell-system resulted in the identification of novel direct or indirect downstream targets of Lmx1a; Grb10, Rgs4 and Vmat2. Therefore, Lmx1a directs neuronal programming inside and outside mdDA neurons.
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