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Melissa H. Kelley, Justin Ortiz, Kaori Shimizu, Himmat Grewal, Nidia Quillinan and Paco S. Herson Alterations in Purkinje cell GABAA receptor pharmacology following oxygen and glucose deprivation and cerebral ischemia reveal novel contribution of β1-subunit-containing receptors European Journal of Neuroscience 37

Article first published online: 26 NOV 2012 | DOI: 10.1111/ejn.12064

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Cerebellar Purkinje cells (PCs) are particularly sensitive to cerebral ischemia and decreased GABAA receptor function following injury is thought to contribute to PC sensitivity to ischemia-induced excitotoxicity. Here we examined the functional properties of the GABAA receptors that are spared following ischemia.

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