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Marine Vernet, Shahid Bashir, Woo-Kyoung Yoo, Jennifer M. Perez, Umer Najib and Alvaro Pascual-Leone Insights on the neural basis of motor plasticity induced by theta burst stimulation from TMS–EEG European Journal of Neuroscience 37

Version of Record online: 28 NOV 2012 | DOI: 10.1111/ejn.12069

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Continuous theta-burst stimulation applied to the motor cortex is a noninvasive brain stimulation protocol suppressing activity in the stimulated area. We show that cTBS (i) modulates a combination of TMS-evoked EEG potentials, providing a measure of excitability; (ii) decreases TMS-induced and increased resting oscillations in theta band, and has the opposite effects in beta band, consistent with hypothetical (de)synchronization mechanisms of active oscillators. Thus, cTBS exerts a complex, system-level impact on the brain.

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