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Makio Torigoe, Kenta Yamauchi, Atsushi Tamada, Ikuo Matsuda, Atsu Aiba, Valérie Castellani and Fujio Murakami Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons European Journal of Neuroscience 37

Version of Record online: 27 MAR 2013 | DOI: 10.1111/ejn.12190

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Axonal projections in the CNS are either crossed or uncrossed. Previous works indicated that Slits/Robos signaling controls the formation of uncrossed projections. Here we show that a mechanism mediated by Neuropilin-2 also regulates the formation of uncrossed projections of midbrain dopaminergic neurons. Interestingly, we found evidence that this mechanism is independent of Sema3s, major ligands for Neuropilin-2, and several other known guidance cues.

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