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Terence Y. Pang, Thibault Renoir, Xin Du, Andrew J. Lawrence and Anthony J. Hannan Depression-related behaviours displayed by female C57BL/6J mice during abstinence from chronic ethanol consumption are rescued by wheel-running European Journal of Neuroscience 37

Version of Record online: 31 MAR 2013 | DOI: 10.1111/ejn.12195

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The presence of depression during rehabilitation from alcohol abuse is associated with a greater chance for relapse, raising the need for methods to prevent depression from developing. In this study, depression-related behaviours detected in mice during abstinence after chronic alcohol consumption are attenuated through engagement in wheel-running. This study supports the use of physical exercise as a simple, low-cost therapeutic intervention as part of a broader rehabilitative program for alcoholism.

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