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Lyes Bachatene, Vishal Bharmauria, Sarah Cattan and Stéphane Molotchnikoff Fluoxetine and serotonin facilitate attractive-adaptation-induced orientation plasticity in adult cat visual cortex European Journal of Neuroscience 38

Article first published online: 15 APR 2013 | DOI: 10.1111/ejn.12206

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Fluoxetine is a widely prescribed drug which is well known for its antidepressant activity by selective inhibition of recapture of serotonin in the brain. Using orientation tuning curve shifts as a model, we show that fluoxetine and serotonin facilitate attractive-adaptation-induced-orientation short-term plasticity in the primary visual cortex without modulating the firing rate of neurons.

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