E-mail

E-mail a Wiley Online Library Link

Christopher C. Lay, Nathan Jacobs, Aneeka M. Hancock, Yi Zhou and Ron D. Frostig Early stimulation treatment provides complete sensory-induced protection from ischemic stroke under isoflurane anesthesia European Journal of Neuroscience 38

Article first published online: 16 APR 2013 | DOI: 10.1111/ejn.12217

Thumbnail image of graphical abstract

Using a rat model of ischemia (permanent middle cerebral artery occlusion; pMCAO) we demonstrate that whisker stimulation can completely protect the cortex from impending stroke. Furthermore, the broad extent of evoked activity evident under isoflurane anesthesia plays a significant role in the protection from, or deterioration towards infarct. We conclude that the pMCAO model may be carried out using isoflurane, allowing for the future investigation of ischemic stroke in awake animals.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH