Kazuhiro Wada, Shin Hayase, Raimu Imai, Chihiro Mori, Masahiko Kobayashi, Wan-chun Liu, Miki Takahasi and Kazuo Okanoya Differential androgen receptor expression and DNA methylation state in striatum song nucleus Area X between wild and domesticated songbird strains European Journal of Neuroscience 38
AR was differentially expressed in striatum Area X GABAergic neurons between wild and domesticated songbird strains having different learned vocal phenotypes. Differences in AR expression were correlated with a song feature related to inter-syllable duration. DNA methylation in AR also differed between strains and within domesticated populations. These results provide insight into the molecular basis of behavioral evolution through the regulation of epigenetic modification.
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