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Yann Pelloux, Jennifer E. Murray and Barry J. Everitt Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats European Journal of Neuroscience 38

Article first published online: 1 JUL 2013 | DOI: 10.1111/ejn.12289

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This study shows that acute impairment of prefrontal cortical function in rats does not result in compulsive cocaine seeking but does influence the propensity to relapse after abstinence. Lesions of the basolateral amygdala result in cocaine seeking in the face of punishment as well as impaired fear conditioning.

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