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A. V. Zaitsev and D. A. Lewis Functional properties and short-term dynamics of unidirectional and reciprocal synaptic connections between layer 2/3 pyramidal cells and fast-spiking interneurons in juvenile rat prefrontal cortex European Journal of Neuroscience 38

Article first published online: 8 JUL 2013 | DOI: 10.1111/ejn.12294

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Synaptic connections between layer 2/3 pyramidal cells and FS interneurons were studied with paired whole-cell recordings in acute neocortical slices of the medial prefrontal cortex from juvenile rats. In the reciprocal connections the amplitude of postsynaptic responses was larger and neurotransmission had a lower failure rate than in the unidirectional connections. The differences between these types of connections persisted during the short-train stimulation.

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