E-mail

E-mail a Wiley Online Library Link

Damian P. Bright and Trevor G. Smart Protein kinase C regulates tonic GABAA receptor-mediated inhibition in the hippocampus and thalamus European Journal of Neuroscience 38

Version of Record online: 16 SEP 2013 | DOI: 10.1111/ejn.12352

Thumbnail image of graphical abstract

PKC activation causes a down-regulation in tonic GABAA receptor-mediated inhibition in hippocampal dentate gyrus granule cells and thalamic dorsal lateral geniculate relay neurons. These findings are corroborated by studying recombinant α4β2δ receptors, which demonstrate a similar inhibition of receptor function, which involves the loss of surface receptors. PKC-mediated phosphorylation is considered an important physiological regulator of tonic GABA inhibition.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH