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Julieta Griselda Mendoza-Torreblanca, América Vanoye-Carlo, Bryan Víctor Phillips-Farfán, Liliana Carmona-Aparicio and Gisela Gómez-Lira Synaptic vesicle protein 2A: basic facts and role in synaptic function European Journal of Neuroscience 38

Version of Record online: 15 SEP 2013 | DOI: 10.1111/ejn.12360

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SV2A protein is important for synaptic function in both normal and pathological conditions. The evidence suggests that SV2A could be a vesicular transporter, regulate synaptic exocytosis as a gel matrix or modulate synaptotagmin-1 (SYT-1) activity. Altered SV2A expression in excitatory and inhibitory synapses causes pathological conditions such as epilepsy.

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