Julieta Griselda Mendoza-Torreblanca, América Vanoye-Carlo, Bryan Víctor Phillips-Farfán, Liliana Carmona-Aparicio and Gisela Gómez-Lira Synaptic vesicle protein 2A: basic facts and role in synaptic function European Journal of Neuroscience 38
SV2A protein is important for synaptic function in both normal and pathological conditions. The evidence suggests that SV2A could be a vesicular transporter, regulate synaptic exocytosis as a gel matrix or modulate synaptotagmin-1 (SYT-1) activity. Altered SV2A expression in excitatory and inhibitory synapses causes pathological conditions such as epilepsy.
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