Tekla Kirizs, Katalin Kerti-Szigeti, Andrea Lorincz and Zoltan Nusser Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells European Journal of Neuroscience 39
Freeze-fracture replica immunogold localisation revealed distinct subcellular distribution patterns for three K+ channel subunits on CA1 pyramidal cells. The Kv1.1 is present in axons, with an ~ 8-fold higher density in AISs than in axon terminals. The Kv2.1 has the same density in AISs, somata and proximal dendrites. The Kir3.2 density increases quasi-linearly from the soma to distal dendrites. Our results predict their differential involvement in synaptic integration and output generation.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf