E-mail

E-mail a Wiley Online Library Link

Dibyendu Chakraborty, Karla K. Rodgers, Shannon M. Conley and Muna I. Naash Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS The FEBS Journal 280

Version of Record online: 22 NOV 2012 | DOI: 10.1111/febs.12055

Thumbnail image of graphical abstract

The second intradiscal loop of the photoreceptor tetraspanin RDS contains mutations which cause widely varying blinding phenotypes. Here we conduct circular dichroism studies of this protein region to understand the effects disease-causing mutations have on the secondary protein structure. The majority of examined mutations cause decreases in the α-helical content of this loop but no change in thermal stability

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH