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Jachen A. Solinger and Anne Spang Tethering complexes in the endocytic pathway: CORVET and HOPS FEBS Journal 280

Article first published online: 21 FEB 2013 | DOI: 10.1111/febs.12151

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Endocytosis and transport through the endosomal system are essential processes involved in cell signaling and cell-cell communication. In this review, we focus the function and regulation of two membrane tethering complexes, CORVET and HOPS, present on endosomal membranes. Although most knowledge to date comes from studies in yeast, we extend our discussion to metazoans.

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