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Tomonari Muramatsu, Yong-Tae Kim, Wataru Nishii, Takaho Terada, Mikako Shirouzu and Shigeyuki Yokoyama Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins The FEBS Journal 280

Version of Record online: 27 MAR 2013 | DOI: 10.1111/febs.12222

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The use of a newly developed method for measuring the activities of the mature and pro-forms of the main protease (Mpro; or 3C-like protease, 3CLpro) of severe acute respiratory syndrome coronavirus (SARS-CoV) revealed important aspects of its autoprocessing mechanism, allowing a numerical simulation of the maturation pathway.

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