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Hanayo Ueoka-Nakanishi, Takashi Sazuka, Yoichi Nakanishi, Masayoshi Maeshima, Hitoshi Mori and Toru Hisabori Thioredoxin h regulates calcium dependent protein kinases in plasma membranes The FEBS Journal 280

Version of Record online: 14 JUN 2013 | DOI: 10.1111/febs.12301

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Thioredoxin (Trx) is a key player in redox homeostasis in plant cells. A calcium-dependent protein kinase 21 (AtCPK21) was identified as a novel Trx target and redox regulation of AtCPK21 by Trx then demonstrated in vitro. Oxidation of AtCPK21 decreased the kinase activity but Trx-h1 effectively restored the activity. An intramolecular disulfide bond Cys97–Cys108 was responsible for this redox modulation.

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