E-mail a Wiley Online Library Link

Shuhei Ishikawa, Yasuhiro Saito, Yoshiki Yanagawa, Satoru Otani, Sachiko Hiraide, Kei-ichi Shimamura, Machiko Matsumoto and Hiroko Togashi Early postnatal stress alters extracellular signal-regulated kinase signaling in the corticolimbic system modulating emotional circuitry in adult rats European Journal of Neuroscience 35

Version of Record online: 15 DEC 2011 | DOI: 10.1111/j.1460-9568.2011.07921.x

Thumbnail image of graphical abstract

The present study elucidated whether early life stress alters the extracellular signal-regulated kinase (ERK) pathway that underlies fear retrieval and fear extinction based on a contextual fear conditioning paradigm, using a juvenile stress model. Levels of phospho-ERK (pERK), the active form of ERK, increased after fear retrieval in the hippocampal CA1 region but not in the medial prefrontal cortex (mPFC).

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field