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Ornella Valenti, Kathryn M. Gill and Anthony A. Grace Different stressors produce excitation or inhibition of mesolimbic dopamine neuron activity: response alteration by stress pre-exposure European Journal of Neuroscience 35

Version of Record online: 18 APR 2012 | DOI: 10.1111/j.1460-9568.2012.08038.x

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Stressors can exert a wide variety of responses, ranging from adaptive responses to pathological changes; moreover, recent studies suggest that mild stressors can attenuate the response of a system to major stressful events. We have previously shown that 2-week exposure to cold, a comparatively mild inescapable stressor, induced a pronounced reduction in ventral tegmental area (VTA) dopamine (DA) neuron activity, whereas restraint stress increases DA neuron activity.

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