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Eiko Nakamaru-Ogiso, Hiroyuki Miyamoto, Kozo Hamada, Koji Tsukada and Katsuji Takai Novel biochemical manipulation of brain serotonin reveals a role of serotonin in the circadian rhythm of sleep–wake cycles European Journal of Neuroscience 35

Version of Record online: 24 MAY 2012 | DOI: 10.1111/j.1460-9568.2012.08077.x

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Serotonin (5-HT) neurons have been implicated in the modulation of many physiological functions, including mood regulation, feeding, and sleep. Impaired or altered 5-HT neurotransmission appears to be involved in depression and anxiety symptoms, as well as in sleep disorders.

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