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Mark D. Humphries and Kevin Gurney Network effects of subthalamic deep brain stimulation drive a unique mixture of responses in basal ganglia output European Journal of Neuroscience 36

Version of Record online: 17 JUL 2012 | DOI: 10.1111/j.1460-9568.2012.08085.x

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Deep brain stimulation (DBS) is a remarkably successful treatment for the motor symptoms of Parkinson’s disease. High-frequency stimulation of the subthalamic nucleus (STN) within the basal ganglia is a main clinical target, but the physiological mechanisms of therapeutic STN DBS at the cellular and network level are unclear.

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