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N. Dehorter, L. Vinay, C. Hammond and Y. Ben-Ari Timing of developmental sequences in different brain structures: physiological and pathological implications European Journal of Neuroscience 35

Version of Record online: 19 JUN 2012 | DOI: 10.1111/j.1460-9568.2012.08152.x

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Brain development is associated with developmental sequences of voltage and transmitter gated currents and network patterns. We compare these sequences in different brain structures and show how they timely shift to behaviourally relevant ones for instance in the basal ganglia to enable targeted locomotion. In keeping with the ‘neuroarcheology’ concept, interruption or alteration of these sequences is a major signature of neurological disorders since neurons keep their immature features.

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