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Marco Tolino, Martin Köhrmann and Michael A. Kiebler RNA-binding proteins involved in RNA localization and their implications in neuronal diseases European Journal of Neuroscience 35

Version of Record online: 19 JUN 2012 | DOI: 10.1111/j.1460-9568.2012.08160.x

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RNA-binding proteins (RBPs) exert crucial functions in mRNA localisation and in the control of local protein synthesis at the activated synapse. In this review, we outline the process of mRNA localisation and the role RBPs play in it. We further discuss how mis-regulation of many of these RBPs are linked to various neuronal diseases and how the latest advances in our understanding encourage early intervention strategies for treatment.

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