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John Cirillo, James Hughes, Michael Ridding, Paul Q. Thomas and John G. Semmler Differential modulation of motor cortex excitability in BDNF Met allele carriers following experimentally induced and use-dependent plasticity European Journal of Neuroscience 36

Version of Record online: 13 JUN 2012 | DOI: 10.1111/j.1460-9568.2012.08177.x

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Up to 50% of healthy people have a specific variation of the brain-derived neurotrophic factor (BDNF) gene that may influence their ability to modify brain connections (i.e. plasticity) under some circumstances. Using non-invasive brain stimulation, we found that motor system plasticity was influenced by the BDNF polymorphism, but the effect was dependent on whether a simple or complex motor task was performed.

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