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Valérie Charbonneau, Marie-Eve Laramée, Virginie Boucher, Gilles Bronchti and Denis Boire Cortical and subcortical projections to primary visual cortex in anophthalmic, enucleated and sighted mice European Journal of Neuroscience 36

Article first published online: 11 JUL 2012 | DOI: 10.1111/j.1460-9568.2012.08215.x

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The cortical afferents to the primary visual cortex were investigated in order to test the hypothesis that the visual cortex receives sensory input from other modalities, and that differences exist in the quantity and/or the structure of projections found in sighted, enucleated and anophthalmic mice. Extensive direct connections are shown between primary visual cortex and auditory and somatosensory, motor and association cortices in all three animal groups. This provides evidence that information from different sensory modalities can be integrated at early cortical stages.

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