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Diana Rien, Roland Kern and Rafael Kurtz Octopaminergic modulation of contrast gain adaptation in fly visual motion-sensitive neurons European Journal of Neuroscience 36

Version of Record online: 9 JUL 2012 | DOI: 10.1111/j.1460-9568.2012.08216.x

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Across different animal classes and sensory modalities neuronal processing was shown to depend on the current state of locomotor activity. In insects, state-dependent release of the neuromodulator octopamine was argued to cause up-regulation of stimulus sensitivity and adjustments of neuronal tuning curves. We show that the octopamine agonist chlordimeform (CDM) enhances the responsiveness of visual motion-sensitive neurons in the blowfly by counteracting contrast-gain adaptation.

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