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Edna Blotnick, Yasmine Hamra-Amitai, Chen Wald, Talma Brenner and Lili Anglister Changes in acetylcholinesterase in experimental autoimmune myasthenia gravis and in response to treatment with a specific antisense European Journal of Neuroscience 36

Version of Record online: 17 JUL 2012 | DOI: 10.1111/j.1460-9568.2012.08218.x

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Controlled regulation of synaptic nicotinic acetylcholine receptors (AChRs) and acetylcholinesterase (AChE), together with maintenance of a dynamic balance between them, is a requirement for proper function of cholinergic synapses. In the present study we assessed whether pathological changes in AChR perturb this balance, and whether such changes can be corrected.

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